Method for removing antigenicity from peptide

Details Method for removing antigenicity from peptide Method for removing antigenicity from peptide

1980-10-02

1981-12-22

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112R, 260118, 2601237, 424 85, 424177, A23J 110, C07G 700, C09H 700

Patent

active

043070132

ABSTRACT:
A method for removing antigenicity from peptide derived from a collagen-containing material or gelatin by hydrolyzing it with aid of an inorganic acid is disclosed. The method is carried out by passing the peptide through a mixture of a cation-exchange resin and an anion-exchange resin. The thus treated peptide may be further passed through a membrane for ultrafiltration to remove pyrogenous substances completely. The peptide obtained is useful as an additive, diluent or carrier for cosmetic articles or drugs.

REFERENCES:
patent: 2669559 (1954-02-01), Reid
patent: 3234199 (1966-02-01), Reid
patent: 4130555 (1978-12-01), Ohtsuka et al.

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