Method for removal of residual organic solvents and use thereof

Details Method for removal of residual organic solvents and use thereof Method for removal of residual organic solvents and use thereof

1998-08-21

1999-11-09

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 45, 546 46, C07D48900, C07D48906

Patent

active

059817518

ABSTRACT:
A method for removing residual organic solvents from a bulk substance, for example from a pharmaceutical drug substance, comprises drying the bulk substance in the presence of water vapor, such that the residual organic solvent molecules are displaced with water vapor molecules.

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patent: 4224371 (1980-09-01), Amiard et al.
patent: 4692519 (1987-09-01), Naito et al.
patent: 5756745 (1998-05-01), Kavka
patent: 5886001 (1999-03-01), Schmidhammer
Stuttgart, ROMPP Chemie Lexikon, 9. Edition, vol. 3 (1990) p. 1886 (XP002085918).
Stuttgart, ROMPP Chemie Lexikon, 9. Edition vol. 4 (1991) p. 3180 (XP002085919).
Merck Index; 10.sup.th Edition; 1983., p. 998.

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