Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1976-03-25
1978-03-21
Meyers, Albert T.
Drug, bio-affecting and body treating compositions
Dentifrices
424 52, 424 57, 424128, 424154, A61K 716, A61K 718, A61K 3342, A01N 1100
Patent
active
040804402
ABSTRACT:
Demineralized tooth enamel is remineralized by first forming a metastable mixture by mixing a solution containing a soluble calcium salt with a solution containing a soluble phosphate salt, the mixture having a pH of from about 2.5 to about 4 and a ratio of calcium ions to phosphate ions of from 0.01 to 100; and second, applying the metastable mixture to the tooth surface. Preferably, the second solution contains a soluble fluoride salt and the metastable mixture has a pH of about 2.7.
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Grabenstetter et al., Chemical Abstracts 81:29518h, (1974).
Levine (1), Arch Oral Biol., vol. 17, pp. 1005-1008, 1972.
Levine (2), Arch. Oral Biol. pp. 1351-1356, (1973).
Levine (3), Brit. Dent. J., pp. 132-134, (1974).
DiGiulio David N.
Grabenstetter Robert J.
Allen George W.
Meyers Albert T.
Mohl Douglas C.
Robinson D. W.
Spector Eric S.
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