Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1991-06-21
1994-12-20
Fleisher, Mindy B.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
536 231, 536 254, 241 2, C12Q 168, C07H 2102, A47J 1906
Patent
active
053745221
ABSTRACT:
A method is disclosed for disrupting cells, including microorganisms, and facilitating thereby the release of cellular components including RNA and DNA into solution. Solutions or suspensions of cells are placed in a container with minute beads of various composition. The container is then placed in an ultrasound bath or otherwise subjected to sonication until the cells disrupt releasing their cellular components, including RNA and DNA. The released RNA and DNA are then available for hybridization with genetic probes.
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Dean Elizabeth D.
Epstein Barry D.
Murphy Kathleen A.
Rosen Ira G.
Fleisher Mindy B.
Gen-Probe Incorporated
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