Method for regulating metabolism with dopamine beta hydroxylase

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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514866, A61F 202

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056268602

ABSTRACT:
Disclosed herein are methods for regulating or ameliorating lipid and glucose metabolism and reducing in a vertebrate animal body fat stores, insulin resistance, hyperinsulinemia, hyperglycemia, hyperlipidemia, elevated blood lipoproteins (such as triglycerides and cholesterol including chylomicrons, VLDL and LDL) and/or increasing in the subject the plasma HDL. The methods comprise administration or timed administration of inhibitors of dopamine beta hydroxylase (DBH).

REFERENCES:
patent: 4659715 (1987-04-01), Meier et al.
patent: 4749709 (1988-06-01), Meier et al.
patent: 4783469 (1988-11-01), Meier et al.
patent: 5006526 (1991-04-01), Meier et al.
Kodama, J. et al. (1990) Effect of Captopril on Glucose Concentration Diebetes Care13:1109-1111.
Torlone, E. et al. (1991) ACE-inhibition increases hepatic and extrahepatic sensitivity to insulin in patients with Type 2(non-insulin-dependent) diabetes mellitus and arterial hypertension Diabetologia34:199-125.
Paolisso, G. et al. (1992) ACE inhibition improves insulin-sensitivity in aged insulin-resistant hypertensive patients Journal of Human Hypertension6:175-179.
Rett, K. et al. (1986) Angiotensin converting enzyme inhibitors in diabetes: experimental and human experience Postgraduate Medical Journal 62(Supp. 1):59-64.
Palatini, P. et al. (1989) Inhibition of dopamine beta-hydroxylase by captopril Biochemical Pharmacology38:1011-1013.
Barnett, Post Graduate Medical J.56:11-14, 1980.
Burns et al., Chronopharmacology and Chronotherapeutics, Intl. Symp. on Chronopharm. and Chronother., Florida A&M Univ. pp. 315-381, 1978.
Cincotta et al., J. Endocrinol.106:173-176, 1985.
Cincotta et al., Ann. Notr. Metab33:305-314, 1989.
Cincotta et al., Experientia43:416-417, 1987.
Eiseman, J. Animal Science59:86-94, 1984.
Eiseman, J. Animal Science59:95-104, 1984.
Emata et al., J. Exp. Zool.233:29-34, 1985.
Harel et al., Proc. La. Acad. of Sci.38:125, 1975.
Joseph et al., Proc. Soc. Exp. Biol. Med.146:1150-1155, 1974.
Komorowski et al., Aliment. Nutr. Metab.1(4):293, 1980.
Larsson et al., La Kartidningen(Sweden) 82(50):4425, 293, 1985.
Martin et al., The Condor75:369-374, 1973.
Martin et al., Chronobiology, "Hormonal Control of Orientation in the White-Throated Sparrow, Zonotrichia Albicollis." pp. 641-646, 1974.
Martin et al., Proc. La. Acad. of Sci.38:127, 1975.
Martin et al., Am. Zoologist18(3):672, 1978.
Martin, D., "Hormonal Regulation of Migratory Orientation in the White-Throated Sparrow, Zonotrichia Albicollis." Diss. LSU, 1974.
Martin, D., "Factors Influencing the Circadian Rhythm of Locomotor Activity in the Anabatoid Fish, Tirchogaster Trichopterus Sumatramus." Thesis. Sam Houston State College, 1969.
Meier et al., Gen & Comp. Endocrinol.Supp 3:499-508, 1972.
Meier et al., Gen & Comp. Endocrinol.26:253-258, 1975.
Meier et al., Current Ornithology2:303-343, 1984.
Meier et al., Experientia48:248-253, 1992.
Meier et al., Gen & Comp. Endocrinol.17:311-318, 1971.
Meier et al., Proc. Soc. Exp. Biol. & Med.137:408-415, 1971.
Meier et al., Science173:1240-1242, 1971.
Meier et al., Physiol. Zool.41(1):95-103, 1968.
Southern et al., J. Anim. Sci.68931-936, 1990.
Wilson et al., Chronobio Int.6:113-121, 1989.
Masukawa et al, "Protection Against Alloxan-Induced Diabetes by Diethyldithiocarbamate and Disulfiram in Mice", Fac. Pharm. Sci, Setsunan Univ., Hirakata, 573-01, Japan Jpn. J. Pharmacol. (1994), 64(3), 141-6 (Abstract).

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