Surgery – Blood drawn and replaced or treated and returned to body – Constituent removed from blood and remainder returned to body
Patent
1982-05-07
1985-02-19
Truluck, Dalton L.
Surgery
Blood drawn and replaced or treated and returned to body
Constituent removed from blood and remainder returned to body
128DIG3, 210646, A61M 103
Patent
active
045003092
ABSTRACT:
An improved hemodialysis method (which may optionally include a hemoperfusion step) including regional extracorporeal citrate anticoagulation is disclosed which permits complete elimination of conventional heparin treatment and possible consequent medical complications from heparin use. The method preferably comprises removing blood from a patient at a level of at least about 80 milliliters per minute, infusing citrate anticoagulant into the blood at a level of up to about 10 millimoles of citrate anion per liter of blood, treating the blood (e.g., by dialysis and hemoperfusion if desired), thereafter infusing a calcium compound into the blood to restore proper calcium ion level and coagulative properties, and returning the blood to the patient. A calcium-free acetate or bicarbonate dialysate is advantageously employed. A charcoal perfusion filter can optionally be used in conjunction with the dialyzer apparatus.
REFERENCES:
patent: 3482575 (1969-12-01), Claff et al.
patent: 3483867 (1969-12-01), Markovitz
patent: 4329986 (1982-05-01), Babb
patent: 4381004 (1983-04-01), Babb
Diederich Dennis A.
Pinnick Robert V.
Wiegmann Thomas B.
The Kansas University Endowment Association
Truluck Dalton L.
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