Method for reducing viral transmission with poly-L-histidine

Details Method for reducing viral transmission with poly-L-histidine Method for reducing viral transmission with poly-L-histidine

1987-01-15

1989-09-05

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, 514967, 514968, 424 54, A61K 3702, C07K 710

Patent

active

048639001

ABSTRACT:
A composition for reducing the transmissability of viral infection from a subject infected therewith which comprises a topically applicable, pharmaceutically acceptable carrier and a viricidally effective amount of a polypeptide of between 24 and 500 aminoacid residues comprising at least 24 residues of L-Histidine.

REFERENCES:
patent: 4725576 (1988-02-01), Pollock et al.
Chem. Abstr., vol. 103, (1985) 142549.
Chem. Abstr., vol. 76, (1972), 100228.
Crumpacker et al., Antimicrobial Agents & Chemotherapy, 15, 642 (1979).
De Clercq et al, Proc. Natl. Acad. Sci. USA, 76, 2947 (1979).
Kern et al., Antimicrobial Agents and Chemotherpay, 13, 344 (1978).

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