Method for reducing unwanted cellular adhesions

Details Method for reducing unwanted cellular adhesions Method for reducing unwanted cellular adhesions

1994-10-07

1996-01-02

Killos, Paul J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A01N 4338

Patent

active

054809010

ABSTRACT:
A conjugate comprising a drug which has an inhibitory effect on cellular adhesion and a lipophilic cell binding agent, when applied to a compromised site, e.g., due to surgical intervention, injury, chemotherapy, disease or inflammation, is effective in reducing unwanted adhesion formation.

REFERENCES:
Carlson R et al Org. Mass Spectrom, (1994) 29(11) 632-40.
Spink, C et al Biochem, Biophys. Acta (1994) 1191(1) 164-72.
DeClerck, L. et al J. Immunol Methods (1994) 172(1) 115-24.

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