Method for reducing the pyrogen content of or removing pyrogens

Details Method for reducing the pyrogen content of or removing pyrogens Method for reducing the pyrogen content of or removing pyrogens

1982-01-27

1983-04-26

Cintins, Ivars C.

Liquid purification or separation

Processes

Ion exchange or selective sorption

210692, B01D 1500

Patent

active

043812392

ABSTRACT:
A method for removing a pyrogen from a solution of a pyrogen-containing substance such as an amino acid, a nucleic acid base, an antibiotic, a hormone, a vitamin, an enzyme, an antibody or the like comprising contacting the solution with an adsorbent to adsorb the pyrogen, which is characterized in that the adsorbent comprises a water-insoluble carrier and a nitrogen-containing heterocyclic compound of the formula:

REFERENCES:
patent: 3959128 (1976-05-01), Harris
patent: 4059512 (1977-11-01), Harris
patent: 4168300 (1979-09-01), Andersson et al.

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