Method for reducing skin irritation associated with drug/penetra

Details Method for reducing skin irritation associated with drug/penetra Method for reducing skin irritation associated with drug/penetra

1988-09-06

1989-08-08

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514424, 514629, 514708, 514724, 514738, 514947, A61K 3155, A61K 3140, A61K 3116, A61K 3110, A61K 31045

Patent

active

048552941

ABSTRACT:
A composition and method for reducing the skin irritation properties of a transdermal drug/enhancer composition which comprises incorporating into said composition, either prior to or at the time of application the skin, an effective amount of glycerin. When incorporated into the drug/enhancer composition prior to application to the skin the glycerin content will be between about 0.1 and 70 wt. %, preferably between about 1.0 and 50 wt. % and most preferably between about 5.0 and 20 wt. % of the composition.

REFERENCES:
patent: 4537776 (1986-08-01), Cooper
patent: 4695465 (1987-09-01), Kigasawa et al.
Remington's Pharmaceutical Sciences, 15th ed., 1975, p. 715.

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