Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1992-11-03
1994-04-19
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424448, 514946, A61F 1300
Patent
active
053043790
ABSTRACT:
A method and means for reducing sensitization or irritation caused by transdermally delivered drugs, wherein one or more metabolic modulators is coadministered with a sensitizing or irritating drug.
REFERENCES:
patent: 3598122 (1971-08-01), Zaffaroni
patent: 3598123 (1971-08-01), Zaffaroni
patent: 4006218 (1977-02-01), Sipos
patent: 4087538 (1978-05-01), Portnoff
patent: 4144317 (1979-03-01), Higuichi et al.
patent: 4286592 (1981-09-01), Chandrasekan
patent: 4314557 (1982-02-01), Chandrasekan
patent: 4379454 (1983-04-01), Campbell et al.
patent: 4440778 (1984-04-01), Matsui et al.
patent: 4559222 (1985-12-01), Enscore et al.
patent: 4573995 (1986-03-01), Cheng et al.
patent: 4573996 (1986-03-01), Kwiatek et al.
patent: 4645774 (1987-02-01), Toth et al.
Lui et al, "Quantitative Mechanistic Studies on Inhibition of Transdermal Metabolism of B-estradiol by Ethanol," Journal of Pharmaceutical Sciences vol. 76, No. 11, Nov. 1987 (abstract).
Drill's Pharmacology in Medicine, ed. Joseph R. DiPalma, Third edition, pp. 41-42 (1965).
Medicinal Chemistry, ed. Alfred Burger, Third edition, pp. 56-57 (1970).
I. S. Severina, "Effect of Alcohols on Mitochondrial Monoamine Oxidase Activity," Bull. Exp. Biol. & Med., 79 (1), pp. 30-32 (1975).
A. Pannatier et al, "The Skin as a Drug-Metabolizing Organ," Drug Metabolism Reviews, 8(2), pp. 319-343 (1978).
E. A. Zeller et al., "How Do MAO-A and MAO-B Select their Substrates? Thermodynamic Aspects," Function and Regulation of Monoamine Enzymes: Basic and Clinical Aspects, E. Usdin et al editors, pp. 469-476 (1981).
C. J. Fowler et al, "Selective Inhibitors of Monoamine Oxidase A and B: Biochemical, Pharmacological, and Clinical Properties," Medicinal Research Reviews, vol. 4, No. 3, pp. 323-358. (1984).
P. K. Noonan, "Cutaneous Metabolism of Xenobiotics," Percutaneous Absorption, R. L. Bronaugh et al., editors, pp. 65-85 (1985).
Goodman and Gilman's, "The Pharmacological Basis of Therapeutics," Seventh edition pp. 13-21 (1985).
Goodman and Gilman's, "The Pharmacological Basis of Therapeutics," Seventh edition, pp. 423-426 (1985).
R. J. Martin et al, "Skin Metabolism of Topically Applied Compounds," International Journal of Pharmaceutics, vol. 39, pp. 23-32 (1987).
D. L. J. Opdyke, Inhibition of Sensitization Reactions induced by Certain Aldehyde FD. Cosmet. Toxicol. vol. 14, pp. 197-198 (1976).
J. D. Guin et al., "The Effect of Quenching Agents on Contact Urticaria Caused by Cinnamic Aldehyde," J. Amer. Aca. Derm., vol. 10, No. 1, pp. 45-51 (1984).
Amkraut Alfred
Cormier Michel J. N.
Ledger Philip W.
Marty Jean P.
ALZA Corporation
Duvall Jean M.
Miller D. Byron
Page Thurman K.
Stone Steven F.
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