Method for reducing sensation in iontophoretic drug delivery

Surgery – Means for introducing or removing material from body for... – Infrared – visible light – ultraviolet – x-ray or electrical...

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128898, 6048901, 607 3, A61N 130

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active

054032750

ABSTRACT:
Methods for delivering therapeutic agents by iontophoresis with reduced or mitigated sensation are disclosed. The methods generally involve the step of delivering therapeutic agent by iontophoresis in the presence of an intentionally added sensation reducing amount of a multivalent ion. Preferred multivalent ions useful to mitigate sensation are calcium, magnesium, phosphate and zinc.

REFERENCES:
patent: 3989816 (1976-11-01), Rajadhyakska
patent: 3991755 (1976-11-01), Vernon et al.
patent: 4141359 (1979-02-01), Jacobsen et al.
patent: 4211222 (1980-07-01), Tapper
patent: 4250878 (1981-02-01), Jacobsen
patent: 4340047 (1982-06-01), Tapper
patent: 4382529 (1983-05-01), Webster
patent: 4398545 (1983-08-01), Wilson
patent: 4405616 (1983-09-01), Rajadkyakska
patent: 4406658 (1983-09-01), Lattin et al.
patent: 4415563 (1983-11-01), Rajadkyakska
patent: 4424210 (1984-01-01), Rajadhyakska
patent: 4744787 (1988-05-01), Phipps et al.
patent: 4747819 (1988-05-01), Phipps et al.
patent: 4752285 (1988-06-01), Petelenz
patent: 5167616 (1992-12-01), Haak et al.
patent: 5221254 (1993-06-01), Phipps
patent: 5246418 (1993-09-01), Haynes et al.
H. Molitor "Experimental Studies on the Causes and Prevention of Iontophoretic Burns", 198 Am. J. Med. Sci. pp. 778-785 (1939).
J. B. Phipps, Abstract of Paper presented Aug. 1989, "The Effect of Extraneous Ions on the Transdermal Iontophoretic Delivery of Hydromorphine".
R. Burnett et al., "Characterization of the Permselective Properties of Excised Human Skin during Iontophoresis", J. Pharm. Sciences, pp. 765-776 (1987).

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