Method for reducing secetion of apolipoprotein B in animals by a

Details Method for reducing secetion of apolipoprotein B in animals by a Method for reducing secetion of apolipoprotein B in animals by a

1997-02-26

1998-11-17

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

A61K 3120

Patent

active

058377336

ABSTRACT:
A method of reducing apolipoprotein B secretion comprises making available to animal cells an amount of conjugated linoleic acid effective to reduce apolipoprotein B secretion from the cells. A related method comprises administering to an animal a safe and effective amount of a conjugated linoleic acid to reduce apolipoprotein B secretion into the animal's bloodstream.

REFERENCES:
patent: 5290684 (1994-03-01), Kelly
patent: 5550034 (1996-08-01), Teng et al.
Haumann, Barbara F., "Conjugated linoleic acid offers research promise," Inform, 7-2:152-159 (1996).
Kisun, N. Lee, et al., "Conjugated linoleic acid and atherosclerosis in rabbits," Atherosclerosis, 108:19-25 (1994).
Nicolosi, Robert J., et al., "Dietary Conjugated Linoleic Acid Reduces Aortic Fatty Streak Formation Greater Than Linoleic Acid in Hypercholesterolemic Hamsters," Abstract, The FASEB Journal, 10-3:A477 (1996).
Nicolosi, Robert J., et al., "Effect of Feeding Diets Enriched in Conjugated Linoleic Acid on Lipoproteins and Aerotic Atherogenesis in Hamsters," Circulation 88 Suppl. 2458 (1993).

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