Method for reducing perception of human underarm odor by a pleas

Details Method for reducing perception of human underarm odor by a pleas Method for reducing perception of human underarm odor by a pleas

1994-03-25

1996-07-23

Dodson, Shelley A.

Drug, bio-affecting and body treating compositions

Anti-perspirants or perspiration deodorants

512 25, A61K 732, A61K 746

Patent

active

055387195

ABSTRACT:
It has now been found that cross-adaptation may occur between two structurally-similar compounds with qualitatively different odors. The perceived intensity of a malodor, for example, underarm sweat, may be decreased by cross-adaptation to at least one ester compound structurally similar to a component of such sweat. Such structurally similar compounds may be used in methods for decreasing the perceived intensity of a malodor such as sweat, in products designed to cover the characteristic odor of sweat, and in methods for covering malodor.

REFERENCES:
Engen, The Perception of Odors, Academic Press, New York (1982); Moncrieff, "Olfactory adaptation and odour likeness," J. Physiol., 133:301-316 (1956).
Cain, "Odor intensity after self-adaptation and cross-adaptation," Percept. Psychophys., 7:271-275 (1970).
Engen & Lindstrom, "Cross-adaptation to the aliphatic alcohols," Amer. J. Psych., 76:96-102 (1963).
Pierce, Wysocki & Aronov, "Mutual cross-adaptation of the volatile steroid . . ." (in Oxford Unversity Press) vol. 13 No. 3 pp. 245-256 (1956).
Todrank, et al., "The effects of adaptation on the perception of similar and dissimilar odors," Chem. Senses, 16:467-482 (1991).
Engen, The Perception of Odors, Academic Press, New York (1982); Moncrieff, "Adaptation--Definition of the Problem," Chapter 4:61-77.
Koster, "Adaptation and cross-adaptation in olfaction," Doctoral dissertation, University of Utrecht (1971).
Zeng, X-N., et al., "An investigation of human apocrine gland secretion for axillary odor precursors," J. Chem. Ecol. 18:1039-1055 (1992).
Zeng, et al., "Analysis of characteristic odors from human male axillae," J. Chem. Ecol. 17:1469-1492 (1991).

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