Method for reducing non-specific aggregation of latex...

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is organic

Reexamination Certificate

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C436S525000, C436S527000, C436S529000, C436S530000, C436S533000, C436S825000, C436S826000

Reexamination Certificate

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06927071

ABSTRACT:
A particle-enhanced assay for determining an analyte in a test sample in which an additive for reducing non-specific particle aggregation is added in an amount to substantially reduce non-specific aggregation. The additive is selected form the group consisting of triethanolamine, trimethanolamine, N-butyldiethanolamine, 3-dimethylamino-2-methylpropyl chloride, N,N-dimethylglycine, N,N-dimethylguanidine, N,N-dimethylglycine ethyl ester, 3-dimethylaminopropionitrile, and N,N-dietylacetamide.

REFERENCES:
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patent: 4536478 (1985-08-01), Sokoloff et al.
patent: 4703001 (1987-10-01), Vodian et al.
patent: 4847209 (1989-07-01), Lewis et al.
patent: 5486479 (1996-01-01), Ito et al.
patent: 5506151 (1996-04-01), Ito et al.
K. Shigenobu et al, Chemical Abstract No. 136: 83390, citing WO 2002/003,068 (Jan. 10, 2002).

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