Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-08-01
2006-08-01
Wilson, James O. (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S046000, C514S047000, C514S049000, C514S050000, C514S051000, C514S912000, C514S913000, C514S762000, C514S763000, C536S025600, C536S026100
Reexamination Certificate
active
07084128
ABSTRACT:
The present invention is directed to a method of reducing intraocular pressure. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a purinerginic receptor ligand, which is a mononucleoside polyphosphate or dinucleoside polyphosphate defined by general Formula I. The method of the present invention is useful in the treatment or prevention of ocular hypertension, such as glaucoma, including primary and secondary glaucoma. The method can be used alone to reduce intraocular pressure. The method can also be used in conjunction with other therapeutic agents or adjunctive therapy commonly used to treat glaucoma to enhance the therapeutic effect of reducing the intraocular pressure.
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Brown Edward G.
Peterson Ward M.
Plourde, Jr. Robert
Yerxa Benjamin R.
Howrey LLP
Inspire Pharmaceuticals Inc.
Kung Viola T.
Owens, Jr. Howard V.
Wilson James O.
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