Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-12-12
1997-12-23
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514255, A61K 31495
Patent
active
057008035
ABSTRACT:
A method for reducing infarct size in a subject afflicted with ischemic heart disease, is disclosed, wherein said method uses, as the active agent, a carbostyril derivative.
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Maruyama et al, "Effects of OPC-8212, a New Positive Inotropic Agent, and Dobutamine on Left Ventricular Global and Ischemic Regional Functions and Coronary Hemodyamics Under Coronary Artery Stenosis", J. Cardiovasc. Pharmacol., 8(1):161-169 (1986).
Takeya et al, "Positive Inotropic Effect of (OPC-8212) and Mechanism of Action in Guinea Pig Ventricular Myocardium", Arzneim.-Forsch./Drug Res., 34(1), Nr.3a:364-370 (1984).
Huang Evelyn
Ivy C. Warren
Otsuka Pharmaceutical Co. Ltd.
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