Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2008-01-29
2008-01-29
Le, Long V. (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S014000, C435S013000, C435S269000
Reexamination Certificate
active
07323315
ABSTRACT:
A method for determining the presence and/or amount of an analyte in a sample of whole blood comprises the step of treating the sample with a nonlytic hypertonic salt composition to reduce the hematocrit by reducing the size of the red blood cells. In optical detection systems, the smaller red blood cells create greater scatter, which allows a more accurate correction to be applied in a dual-wavelength detection system. In electrochemical detection systems, as well as in optical detection systems, the smaller red blood cells provide less obstruction to the diffusion of analyte and reagents in the sample, to facilitate the reactions thereof.
REFERENCES:
patent: 4935346 (1990-06-01), Phillips
patent: 5049394 (1991-09-01), Howard
patent: 5049487 (1991-09-01), Phillips
patent: 5179005 (1993-01-01), Phillips et al.
patent: 5304468 (1994-04-01), Phillips
patent: 5306623 (1994-04-01), Kiser et al.
patent: 5789255 (1998-08-01), Yu
patent: 5948695 (1999-09-01), Douglas et al.
patent: 6190918 (2001-02-01), Chu et al.
patent: 1 202 059 (2002-05-01), None
patent: 1 202 061 (2002-05-01), None
patent: 01262470 (1989-10-01), None
patent: HEI1-262470 (1989-10-01), None
patent: 09105750 (1997-04-01), None
patent: WO 01/57239 (2001-08-01), None
patent: WO 02/14535 (2002-02-01), None
Red Cell Volume in Glycerol/Sodium Chloride/Water Mixtures, Brief Communications, Cryobiology 21, pp. 234-239 (1984).
European Search Report, Nov. 8, 2005.
Bayer Healthcare LLC
Le Long V.
Nixon & Peabody LLP
Yang N
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