Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2011-03-29
2011-03-29
Swope, Sheridan (Department: 1652)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S300000
Reexamination Certificate
active
07915219
ABSTRACT:
Peptides able to inhibit or activate the translocation or function of δPKC are identified. Administration of the peptides for protection or enhancement of cell damage due to ischemia is described. Therapeutic methods to reduce damage to cells or to enhance damage to cells due to ischemia are also described, as well as methods for screening test compounds for δPKC-selective agonists and antagonists.
REFERENCES:
patent: 4708871 (1987-11-01), Geysen
patent: 5776716 (1998-07-01), Napolitano et al.
patent: 5783405 (1998-07-01), Mochly-Rosen et al.
patent: 6165977 (2000-12-01), Mochly-Rosen
patent: 6664040 (2003-12-01), Sherman et al.
patent: 6855693 (2005-02-01), Mochly-Rosen et al.
patent: 7265092 (2007-09-01), Li
patent: 7563772 (2009-07-01), Mochly-Rosen et al.
patent: 2004/0204364 (2004-10-01), Mochly-Rosen et al.
patent: 2008/0075706 (2008-03-01), Li
patent: 2009/0062208 (2009-03-01), Mochly-Rosen et al.
patent: 2009/0075901 (2009-03-01), Mochly-Rosen et al.
patent: 2009/0186814 (2009-07-01), Ikeno et al.
patent: 2009/0192089 (2009-07-01), Mochly-Rosen et al.
patent: WO-97/14038 (1997-04-01), None
patent: WO-2009/029678 (2009-03-01), None
Del Zoppo, Clinical trials in acute stroke: why have they not been successful? Neurology. Sep. 1998;51(3 Suppl 3):559-61.
USPTO in house BLAST alignment; Seq ID No. 4 vs human PKCdelta (NP—006245.2). Performed Aug. 4, 2010.
Daria Mochly-Rosen, List of peptides provided for experimental use sent to Lobo Lab, University of California, San Francisco, San Francisco, California, US. Feb. 11, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Sailen Barik, Department of Biochemistry and Molecular Biology, University of Southern Alabama, Mobile, Alabama, US Mar. 19, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Derek Miles Yellon, Hatter Institute for Cardiovascular Studies, Department of Academic and Clincial Cardiology, University of College Hospital and Medical School, London, UK Jun. 25, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Derek Miles Yellon, Hatter Institute for Cardiovascular Studies, Department of Academic and Clincial Cardiology, University of College Hospital and Medical School, London, UK Oct. 14, 1998.
Email to Dr. Dr. Derek Miles Yellon, Hatter Institute for Cardiovascular Studies, Department of Academic and Clincial Cardiology, University of College Hospital and Medical School, London, UK Oct. 14, 1998.
Email to Dr. Dr. Derek Miles Yellon, Hatter Institute for Cardiovascular Studies, Department of Academic and Clincial Cardiology, University of College Hospital and Medical School, London, UK Aug. 9, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Fiorenzo Battaini, Institute of Pharmacological Sciences, University of Milano Milano, IT, Oct. 15, 1998.
Email from Fiorenzo Battaini, Aug. 14, 1998.
Fiorenzo Battaini, Letter outling project, Aug. 14, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Ashwani Malhotra, Cardiovascular Research Institute, New York Medical Colloge, Valhalla, New York, US. Oct. 16, 1998.
Ashwanu Malhotra, List of peptides provided for expermiental use sent to Dr. Ashwani Malhotra, Cardiovascular Research Institute, New York Medical College, Valhalla, New York, US, Oct. 16, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Naoaki Saito, Laboratory of Molecular Pharmacology, Biosignal Research Center, Kobe University, Kobe, JP, Oct. 15, 1998.
Naoaki Saito, Email requesting peptidesList of peptides provided for expermiental use sent to Dr. Naoaki Saito, Laboratory of Molecular Pharmacology, Biosignal Research Center, Kobe University, Kobe, JP, Oct. 15, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Mohamed Boutjdir, Department of Cardiology, VA Medical Center, Brooklyn, New York, US, Aug. 14, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Drs. Rik Derynck and Huizhou Fan, Department of Growth and Development, University of California, San Francisco, San Franciso, California, US, Oct. 27, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Drs. Rik Derynck and Huizhou Fan, Department of Growth and Development, University of California, San Francisco, San Franciso, California, US, Oct. 26, 1998.
Purchase Order for PKC peptides, Department of Growth and Development, University of California, San Francisco, San Francisco, California, US. Oct. 26, 1998.
Daria Mochly-Rosen, Material Transfer Agreement and List of peptides provided for expermiental use sent to Drs. Rik Derynck and Huizhou Fan, Department of Growth and Development, University of California, San Francisco, San Francisco, California, US, Oct. 26, 1998.
Daria Mochly-Rosen, Email regarding request for peptides for expermiental use from Drs. Rik Derynck and Huizhou Fan, Department of Growth and Development, University of California, San Francisco, San Francisco, California, US, Sep. 11, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Marsha Rosner, Department of Pharmacological and Physiological Sciences, University of Chicago, Chicago, Illinois, US, Nov. 17, 1998.
Daria Mochly-Rosen, Email regarding request for peptides for expermiental use from Dr. Marsha Rosner, Oct. 27, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. John Hayslett, Yale School of Medicine, New Haven, Conneticut, US, Dec. 14, 1998.
John Hayslett, Letter of Dr. Mochly-Rosen requesting peptides, Oct. 28, 1998.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Guang S. Liu, Department of Physiology, University of South Alabama, Mobile, Alabama, US, Nov. 23, 1998.
Daria Mochly-Rosen, signed Material Transfer Agreement with Dr. Steven Pelech, Department of Medicine, University of British Columbia, Vancouver, B.C., CA, Feb. 10, 1999.
Daria Mochly-Rosen, Email to Dr. Steven Pelech regarding peptides, Feb. 8, 1999.
Daria Mochly-Rosen, Material Transfer Agreement to Dr. Pedro A. Jose, Georgetown University Hospital, Washington, D.C., US, Feb. 17, 1999.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Rafael Nesher, Department of Endocrinology, University of South Alabama, Mobile, Alabama, US, Feb. 10, 1999.
Daria Mochly-Rosen, Email to Dr. Rafael Nesher regarding peptides, Feb. 8, 1999.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Chaya Brodie, Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel, Mar. 11, 1999.
Email traffic between Drs. Mochly-Rosen and Brodie regarding peptides.
Daria Mochly-Rosen, Material Transfer Agreement to Dr. Chaya Brodie, Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel, Mar. 11, 1999.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Mireia Gomez-Angelats, National Institute of Environmental Health Sciences, RTP, NC, US, Jul. 13, 1999.
Email traffic between Drs. Mochly-Rosen and Gomez-Angelats regarding peptides, Jun. 18, 1999.
Daria Mochly-Rosen, Material Transfer Agreement to Dr. Cindy Miranti, Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, US, Nov. 30, 1999.
Daria Mochly-Rosen, Material Transfer Agreement to Dr. Alexei Kourakine, Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, US, Nov. 30, 1999.
Che-Hong Chen, List of peptides provided for expermiental use sent to Dr. Karen M. Ridge, Northwestern University, Chicago, Illinois, Apr. 4, 2000.
Email traffic between Drs. Mochly-Rosen and Yuri Volkov, SPD Research Laboratory, The Trinity Centre for Health Sciences, St. James Hospital, Dublin, Ireland, Jun. 18, 1999.
Che-Hong Chen, Material Transfer Agreement and supporting documents to Dr. Steve Black, Department of Pediatrics, University of California, San Francisco, California, US, Sep. 3, 1998.
Daria Mochly-Rosen, Material Transfer Agreement to Dr. Umberto Kucich, School of Dental Medicine, Department of Anatomy and Histology, Ph
Chen Leon E.
Mochly-Rosen Daria
Morrison & Foerster / LLP
Swope Sheridan
The Board of Trustees of the Leland Stanford Junior University
LandOfFree
Method for reducing central nervous system tissue or cell... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for reducing central nervous system tissue or cell..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for reducing central nervous system tissue or cell... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2749961