Method for reducing cardiovascular morbidity and mortality...

Details Method for reducing cardiovascular morbidity and mortality... Method for reducing cardiovascular morbidity and mortality...

2008-07-29

2008-07-29

Tsang, Cecilia J. (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

Reexamination Certificate

active

07405196

ABSTRACT:
This invention relates to a method of reducing cardiovascular morbidity and mortality in a prediabetic or Type 2 Diabetes patient population. The method comprises administering an effective dosage of a long acting insulin, preferably insulin glargine, to a prediabetic or Type 2 Diabetes patient.

REFERENCES:
Costa et al. “Impaired Glucose Tolerance”, 2002, Treat Endocrinol. vol. 1, pp. 205-210.
‘Medscape: Impaired Fasting Glucose and Impaired Glucose Tolerance: Implications for Care’ [online], Mar. 13, 2007 [retrieved on Apr. 7, 2007. Retrieved from the internet: <URL:http://www.medscape.com/viewarticle/553218>.
Rosenstock, J., et. al, Basal Insulin Therapy in Type 2 Diabetes: 28-week Comparison of Insulin Glargine (HOE 901) and NPH Insulin, Abstract XP002282639 Medline Diabetes Care Apr. 2001 vol. 24, No. 4 pp. 631-636.
Thomas, M., et. al., Evaluation of the Safety, Efficacy and Tolerability of Insulin Glargine in Subjects with Impaired fasting Glucose, Impaired Glucose Tolerance or New-Onset Type 2 Diabetes, Abstract Biosis/Biosis vol. 52, No. Supplement 1, 2003 pp. A451-A452 XP002282638.
Turner, R., et. al. Beta-Cell function Improved by Supplementing Basal Insulin Secretion In Mild Diabetes, British Medical Journal May 22, 1976, vol. 1, No. 6020 pp. 1252-1254 XP009031347.

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