Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.
Patent
1989-08-28
1991-09-10
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Hormones, e.g., prolactin, thymosin, growth factors, etc.
530350, 530419, 530421, 435 694, 435 691, C07K 1514, C07K 1506, C07K 324
Patent
active
050475118
ABSTRACT:
A method for recovering a recombinant protein from a protein solution containing high molecular weight contaminating proteins by directly adding a flocculant to the solution in amounts sufficient to selectively precipitate the high molecular weight protein contaminants is disclosed.
The high molecular weight precipitates are removed and the solution is further processed to remove low molecular weight contaminating proteins and other non-protein contaminants. The recombinant protein is subsequently recovered and further processed to produce a protein composition suitable for its intended use.
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Kirk-Othmer Encyclopedia of Chemical Technology, vol. 19, p. 531.
Farquer Thomas L.
Furman Keith C.
Guffey Wendell R.
Moskowitz Margaret
Pitman-Moore Inc.
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