Method for recovering myeloperoxidase and pharmaceutical composi

Details Method for recovering myeloperoxidase and pharmaceutical composi Method for recovering myeloperoxidase and pharmaceutical composi

1981-08-28

1983-04-05

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

A61K 3748

Patent

active

043791417

ABSTRACT:
Myeloperoxidase can be separated and recovered from a supernatant liquid of an aqueous dispersion of a disintegration product of human myelogenous leukocytes, which dispersion has been admixed with at least one member selected from the group consisting of manganese salts and protamine sulfate. The recovered myeloperoxidase in combination with an alkali metal halide can be used as a pharmaceutical composition effective against microorganisms deficient or diminished in catalase synthesizing activity.

REFERENCES:
Chemical Abstracts, 73, 117541a (1970).
Jacobs et al., "Biochemical and Biophysical Research Communications", 39 (2), 284-289 (1970).

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