Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving blood clotting factor
Patent
1982-10-28
1986-07-01
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving blood clotting factor
530381, 435 23, 435212, C12Q 156, C07K 508
Patent
active
045980438
ABSTRACT:
A method for assaying blood coagulation factor XII in human blood plasma wherein plasma is treated with an activator in order to convert factor XII present in the plasma into factor XIIa, the latter is reacted with a tripeptide derivative which is split by the enzymatic action of factor XIIa and forms a colored or fluorescent split product, and the quantity of this split product is measured photometrically, spectrophotometrically or fluorescence-spectrophotometrically.
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Chemical Abstracts, vol. 98, p. 217, 1983, abstract No. 2358v: Ohishi, S., "Fluid Phase Activation of Hageman Factor (Factor XII) in Citrated Human Plasma by Bromelain: An Application to the Indirect Enzymatic Assay for Hageman Factor".
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Moskowitz M.
Pentapharm AG
Wiseman Thomas G.
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