Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-11-08
2005-11-08
Chin, Chris (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S001100, C435S007210, C435S007230, C435S007240, C435S007920, C435S040510, C435S040520, C435S363000, C435S373000, C435S395000, C435S284100, C435S287900, C436S063000, C436S064000, C436S544000, C436S546000, C436S010000, C436S015000, C436S056000, C436S164000, C436S166000, C436S171000, C436S172000, C422S052000, C422S051000, C422S062000, C422S073000, C422S082050, C422S082070
Reexamination Certificate
active
06962789
ABSTRACT:
The present invention provides a method for determining expression levels of one or a multiplicity of target proteins in a tissue or cell sample.
REFERENCES:
patent: 5008185 (1991-04-01), Bacus
patent: 5086476 (1992-02-01), Bacus
patent: 5109429 (1992-04-01), Bacus et al.
patent: 5202931 (1993-04-01), Bacus
patent: 5514554 (1996-05-01), Bacus
patent: 5846749 (1998-12-01), Slamon et al.
patent: 5998151 (1999-12-01), Johnston et al.
patent: 6007996 (1999-12-01), McNamara et al.
patent: 6165734 (2000-12-01), Garini et al.
patent: 6463438 (2002-10-01), Veltri et al.
patent: 0378 383 (1990-07-01), None
patent: WO 93 03741 (1993-03-01), None
patent: WO 00/23799 (2000-04-01), None
Bacus et al., Archives of Pathology and Laboratory Medicine, vol. 114, No. 2, 1990, pp. 164-169.
Bacus et al., American Journal of Pathology, vol. 137, No. 1, Jul. 1990, pp. 103-111.
Van Diest et al., Analytical Cellular Pathology, vol. 3, No. 4, 1991, pp. 195-202.
Muss et al., 1994, N. Engl. J. Med. 330:1260-66.
Kraus et al., 1989, Proc. Natl. Acad. Sci. U.S.A. 86:9193-97.
Mendelsohn, 1990, Semin. Cancer Biol. 1:339-44.
Hancock et al., 1991, Cancer Res. 51:4575-80.
Peles et al., 1991, EMBO J. 10:2077-86.
Arteaga et al., 1994, Cancer Res., 54:3758-65.
Pietras et al., 1994, Oncogene 9:1829-38.
Cobleigh et al., 1999, J. Clin. Oncol. 17:2639-48.
Vincent et al., 2000, Cancer Chemother. Pharmacol. 45:231-38.
Lowry et al., 1951, J. Biol. Chem. 193:265-275.
Bacus et al., “Potential use of Image Analysis for the Evaluation of Cellular Predicting Factors for Therapeutic Response in Breast Cancers”, Analytical and Quantitative Cytology and Histology, vol. 19 No. 4, Aug. 1997, pp. 316-328.
Bacus et al., “HER-2
eu oncogene expression, DNA ploidy and proliferation index in breast cancer”, Analytical and Quantitative Cytology and Histology, vol. 14, No. 6, 1992 pp. 433-445.
Bacus et al., “HER-2/NEU Oncogene Expression and DNA Ploidy Analysis in Breast Cancer”, American Journal of Pathology, vol. 114, No. 2, 1990, pp. 164-169.
Bacus et al., “HER-2/Neu oncogene expression and proliferation in breast cancer”, American Journal of Pathology, vol. 137, No. 1—Jul. 1990.
Cobleigh et al., “Multinational Study of the Efficacy and Safety of Humanized Anti-HER2 Monoclonal Antibody in Women Who Have HER2-Overexpressing Metastatic Breast Cancer That Has Progressed After Chemotherapy for Metastatic Disease”, 1999, J. Clin. Oncol. 17:2639-48.
Hancock et al., “A Monoclonal Antibody against the c-erbB-2 Protein Enhances the Cytotoxicity of cis-Dianninedichloroplatinum against Human Breast and Ovarian Tumor Cell Lines”, 1991, Cancer Res. 51:4575-80.
Kraus et al., “Isolation and Characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors”, 1989, Proc. Natl. Acad. Sci. U.S.A. 86:9193-97.
Lowry et al., “Protein Measurement with the Folin Phenol Reagent”, 1951, J. Biol. Chem. 193:265-275.
Mendelsohn, “The epidermal growth factor receptor as a target for therapy with antireceptor monoclonal antibodies” 1990, Semin. Cancer Biol. 1:339-44.
Muss et al., “c-erbB-2 Expression and Response to Adjuvant Therapy in Women with Node-Positive Early Breast Cancer”, 1994, N. Engl. J. Med. 330:1260-66.
Peles et al., “Oncogenic Forms of the Neu/HER2 Tyrosine Kinase are Permanently Coupled to Phospholipase Cy”, 1991, EMBO J. 10:2077-86.
Peles et al., “Isolation of the Neu/HER-2 Stimulatory Ligand: A 44 kd Glycoprotein That Induces Differentiation of Mammary Tumor Cells”, 1992, Cell 69:205-16.
Pietras et al., “Antibody to HER-2
eu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cell”, 1994, Oncogene 9:1829-38.
Van Diest et al., “Quantitation of HER-2
eu oncoprotein overexpression in invasive breast cancer by image analysis: a study comparing fresh and paraffin-embedded material”, Analytical Cellular Pathology, vol. 3, No. 4, 1991, pp. 195-202.
Vincent et al., “Anticancer efficacy of the Irreversible EGFr Tyrosine Kinase Inhibitor PD 0169414 Against Human Tumor Xenografts”, 2000, Cancer Chemother. Pharmacol. 45:231-38.
DiGiovanna, 1999, PPO Updates: Princ. Practice Oncol. 13:1-9.
Shak, 1999, Semin. Oncol. 26:71-77.
Sliwkowski et al., 1999, Semin. Oncol. 26:60-70.
Chin Chris
Gabel Gailene R.
McDonnell Boehnen & Hulbert & Berghoff LLP
Ventana Medical Systems, Inc.
LandOfFree
Method for quantitating a protein by image analysis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for quantitating a protein by image analysis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for quantitating a protein by image analysis will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3497412