Method for quantifying optical properties of the human lens

Optics: eye examining – vision testing and correcting – Eye examining or testing instrument – Methods of use

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351205, 351221, A61B 300

Patent

active

058943404

ABSTRACT:
Method for quantifying optical properties of the human lens. The present invention includes the application of fiberoptic, OMA-based instrumentation as an in vivo diagnostic tool for the human ocular lens. Rapid, noninvasive and comprehensive assessment of the optical characteristics of a lens using very modest levels of exciting light are described. Typically, the backscatter and fluorescence spectra (from about 300- to 900-nm) elicited by each of several exciting wavelengths (from about 300- to 600-nm) are collected within a few seconds. The resulting optical signature of individual lenses is then used to assess the overall optical quality of the lens by comparing the results with a database of similar measurements obtained from a reference set of normal human lenses having various ages. Several metrics have been identified which gauge the optical quality of a given lens relative to the norm for the subject's chronological age. These metrics may also serve to document accelerated optical aging and/or as early indicators of cataract or other disease processes.

REFERENCES:
patent: 5303026 (1994-04-01), Strobl et al.
patent: 5369496 (1994-11-01), Alfano et al.
Joseph A. Zuclich et al., "Rapid Noninvasive Optical Characterization of the Human Lens," Lasers in the Life Sciences 6(1), 39 (1994).

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