Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Separation or purification
Reexamination Certificate
2008-07-29
2008-07-29
Saucier, Sandra E. (Department: 1651)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Separation or purification
C530S317000, C530S332000, C435S085000
Reexamination Certificate
active
10621353
ABSTRACT:
Disclosed is a method for purifying teicoplanin A2comprising: (i) a primary pre-purification step of purifying a filtrate of fermentation broth of a strain using a synthetic adsorbent; (ii) a secondary pre-purification step of purifying the primary pre-purification solution using a cation exchange resin having a high cross-linkage, a catalytic resin or a chelate resin; (iii) a final purification step of purifying the secondary pre-purification solution using a reversed phase resin; and (iv) a powder-forming step. According to the present invention, it is possible to obtain teicoplanin A2with a higher purity through a relatively simple process without using an excessive amount of an organic solvent.
REFERENCES:
patent: 4239751 (1980-12-01), Coronelli et al.
patent: 4542018 (1985-09-01), Borghi et al.
patent: 4594187 (1986-06-01), Strazzolini et al.
patent: 4845194 (1989-07-01), Glass et al.
patent: 5539087 (1996-07-01), Restelli et al.
patent: 6391851 (2002-05-01), Sawai et al.
patent: 479086 (1995-09-01), None
patent: 200066479 (2000-11-01), None
Parenti et al., “Teichomycins, New Antibiotics fromActinoplanes teichomyceticusNov. Sp.”, The Journal of Antibiotics, Apr. 1978, pp. 276-283.
Choi Byoung-Taek
Choi Gang-Sun
Choi Yong-Rack
Hwang Sung-Ho
Kang Tae-Won
CKD BIO Corp.
Greenblum & Bernstein P.L.C.
Hanley Susan
Saucier Sandra E.
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