Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1987-11-19
1989-07-11
Kight, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530384, 530412, 530415, 210656, 210927, 514822, 424101, C07G 700, A61K 3514, A61K 3516, C07K 320
Patent
active
048473626
ABSTRACT:
The present invention relates to a high-recovery, high-resolution method for purifying antihemophilic factor by using column chromatography techniques in the presence of sugars, polyhydric alcohols, amino acids or salts.
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Lundblad et al., "The Effect of Dextrose on Chromatography of Antihemophilic Factor (Factor VIII)", Thrombosis Research, 1:197, (1972).
Austen et al., "Factor VIII Fractionation on Aminohexyl Sepharon With Possible Reduction in Hepatitis B Antigen", Thromb. Haemstas, 48(1):46, (1982).
Faure et al., "Improved Buffer for the Chromatographic Separation of Factor VIII Coagulant", J. Chromatog: 257:387, (1983).
Johnson Alan J.
Mathews Rita W.
Kight John
New York University
Nutter Nathan M.
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