Method for purifying and isolating two ionic forms of somatomedi

Details Method for purifying and isolating two ionic forms of somatomedi Method for purifying and isolating two ionic forms of somatomedi

1986-08-07

1988-09-06

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530324, A61K 3724, C07K 710

Patent

active

047693614

ABSTRACT:
Two different ionic forms of somatomedin C (pI 6.4-7.0 and pI 8.3-8.6) are separated and isolated by applying an aqueous solution of somatomedin C to a strong cation-exchange column, eluting the somatomedin C from the column by applying a salt concentration gradient at constant pH and recovering the two ionic forms in different eluant fractions.

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