Method for purifying a crude tissue plasminogen activator prepar

Details Method for purifying a crude tissue plasminogen activator prepar Method for purifying a crude tissue plasminogen activator prepar

1992-02-28

1992-10-27

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435212, 435815, C12N 964, C12N 948

Patent

active

051588820

ABSTRACT:
Separation of tPA and undesired proteins is securely and effectivity accomplished by using a cation-exchanger in the two step procedure for selective elution of undesired proteins from the cation-exchanger on which tPA and undesired proteins are adsorbed: undesired proteins having the pI equivalent to or lower than that of tPA was eluted out in the first step and then undesired proteins having the pI equivalent to or higher than were eluted in the second step.

REFERENCES:
patent: 4104125 (1978-08-01), Takechi et al.
patent: 4264738 (1981-04-01), Stepanov et al.
patent: 4374926 (1983-02-01), Stern
Scopes, "Protein Purification Principles and Practice", 2nd edition, 1987, pp. 110, 111, 122, 123.

Affiliated with

Also associated with

Rating

Method for purifying a crude tissue plasminogen activator prepar does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for purifying a crude tissue plasminogen activator prepar, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for purifying a crude tissue plasminogen activator prepar will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-905167