Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Separation or purification
Reexamination Certificate
2007-03-20
2007-03-20
Gupta, Anish (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Separation or purification
C530S412000, C530S413000, C549S263000, C549S299000, C549S300000, C549S200000
Reexamination Certificate
active
09839696
ABSTRACT:
Purification of poly-amino acid-tagged recombinant proteins has been improved by the use of a carboxymethylated aspartate ligand complexed with a third-block transition metal having an oxidation state of 2+and a coordination number of 6. A method for synthesizing the metal ion-CM-Asp complex is also described. Further, the metal ion-CM-Asp complex can be used for screening protein function.
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Nelson Paul S.
Perry Brian
Smith Thomas H.
Yang Te-Tuan
Bozicevic Field & Francis LLP
Clontech Laboratories, Inc.
Field Bret E.
Gupta Anish
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