Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1996-12-30
1998-10-06
Walsh, Stephen
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 12, 530350, 530399, A61K 3800, A61K 3818, A61K 3817, A61K 3816
Patent
active
058176225
ABSTRACT:
A novel growth factor, neurturin, is disclosed. The human and mouse amino acid sequences have been identified. Human and mouse neurturin genomic DNA sequences have been cloned and sequences and the respective cDNA sequences identified. The subcloning into vectors and the preparation of cells stably transformed with the vectors is also disclosed. In addition, methods for treating degenerative conditions using neurturin, methods for detecting gene alterations and methods for detecting and monitoring patient levels of neurturin are provided. Methods for identifying additional members of the neurturin-GDNF family of growth factors are also provided.
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Johnson, Jr. Eugene M.
Kotzbauer Paul T.
Lampe Patricia A.
Milbrandt Jeffrey D.
Pak Michael
Walsh Stephen
Washington University
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