Method for providing nutritional requirements to patients having

Details Method for providing nutritional requirements to patients having Method for providing nutritional requirements to patients having

1992-11-05

1994-10-18

Henley, III, Raymond J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514561, 514565, 426 2, A61K 3700, A61K 31195, A23L 1305

Patent

active

053568737

ABSTRACT:
The present invention relates to methods for providing nutritional requirements to a patient having a chronic inflammatory reaction by administering to the patient an enteral composition that has a sufficiently reduced arginine content to reduce the nitric oxide formation in the patient. In an embodiment, the composition includes less than approximately 0.2% of the total calories as arginine.

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patent: 4752618 (1988-06-01), Mascioli et al.
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patent: 5028627 (1991-07-01), Kilbourn et al.
patent: 5055446 (1991-10-01), Alexander et al.
patent: 5158883 (1992-10-01), Griffith
Bone et al., Definitions for sepsis and organ failure, Critical Care Medicine, vol. 20, No. 6, pp. 724-725 (1992).
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis, Critical Care Medicine, vol. 20, No. 6, pp. 864-874 (1992).
Kilbourn et al., Inhibition of Interleukin-1-.alpha.-Induced Nitric Oxide Synthase in Vascular Smooth Muscle and Full Reversal of Interleukin-1-.alpha.-Induced Hypotension by N.sup..omega. -Amino-L-arginine, Journal of the Nat'l. Cancer Institute, vol. 84, No. 13, pp. 1008-1016 (1992).
Remington's Pharmaceutical Sciences 16th edition, (1980) p. 396.

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