Method for prophylactic treatment of the colonization of a Staph

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 8, 514 12, 424 92, 435825, 435849, 435882, 435883, 435884, 435885, A01N 3718, A01N 3700, C12N 100, C12N 120

Patent

active

051890151

ABSTRACT:
A method for prophylactic treatments of the colonization of a Staphylococcus aureus bacterial strain having the ability to bind to fibronectin in a mammal. The method comprises administering a prophylactic therapeutically active amount of a protein having fibronectin binding properties to a mammal in need of such treatment. The generation of infections, such as mastitis, caused by a Staphylococcus aureus bacterial strain are thereby prevented. The administration may be via vaccination to induce immunization.

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patent: 4784989 (1988-11-01), Hook et al.
Espersen et al. Inf & Inm, 37, 1982, "Isolation of a Fibronectin Binding Protein from Staphylococcus aureus", pp. 526-531.
Ryden et al (1983), JBC 258:3396-3401, "Fibronectin Receptors from Staphylococcus Aureus".
Keil-Dlouha et al (1983), Biochem Biophys Acta 727:115-21, "Cell-Surface Collagen-Binding Protein in the Procaryote Achromobacter iophagus".

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