Method for propagating influenza virus

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

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Reexamination Certificate

active

07883844

ABSTRACT:
A method for producing influenza virus on large scale is provided. A method for propagating influenza virus which comprises, after removing or decreasing a trypsin inhibitor secreted into culture of MDCK cells (cell line derived from dog kidney) by washing with a culture medium or a buffer, inoculating influenza virus into said cells and culturing said influenza virus-inoculated cells in a culture medium supplemented with trypsin.

REFERENCES:
patent: 4500513 (1985-02-01), Brown et al.
patent: 6656720 (2003-12-01), Groner et al.
patent: 2003/0044962 (2003-03-01), Makizumi et al.
patent: 153723 (1980-11-01), None
patent: 201574 (1987-09-01), None
patent: 509081 (1999-08-01), None
patent: 507825 (2000-06-01), None
patent: 96/15232 (1996-05-01), None
patent: 97/37000 (1997-10-01), None
patent: 97/37001 (1997-10-01), None
patent: 0164846 (2001-09-01), None
patent: 2005/026333 (2005-03-01), None
patent: 2006/051946 (2006-05-01), None
Genzel et al, Vaccine, 2006, vol. 24, pp. 3261-3272.
Orstavik., “Susceptibility of Continuous Lines of Monkey Kidney Cells to Influenza and Parainfluenza Viruses in the presence of trypsin” Acta path. microbiol. scand. Sect. B, 89: 179-183 (1981).
Kido et al., “Pulmonary surfactant is a potential endogenous inhibitor of proteolytic activation of Sendai virus and influenza A virus” Federation of European Biochemical Societies, vol. 322(2):115-119 (1993).
Yamaoka et al., “MDCK cell cultures supplemented with high concentrations of trypsin exhibit remarkable susceptibility to influenza C virus” Arch Virol,140:937-944 (1995).
Merten et al., Production of influenza virus cell cultures for vaccine preparation, Advances in Experimental Medicine and Biology, 397:141-151 (1996).
Merten et al., Production of influenza virus in serum-free mammalian cell cultures, Developements in Biological Standardization, 98:23-37 (1997).
Merten et al., The new medium MDSS2N, free of any animal protein supports cell growth and product of various viruses, Cytotechnology, 30(1-3):191-201 (1999).
Kessler et al., Suitability of MDCK cells grown in a serum-free medium for influenza virus protection, Developements in Biological Standardization, 98:13-21 (1999).
Mancini et al., Avaliacao DA tripsina na multiplicacao devirus influenza em culturas MDCK, Revista de Farmacia E Bioquimica Da Universidade De Sao Paulo, 29(2):89-95 (1993).

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