Method for promoting tissue adhesion to soft tissue implants

Details Method for promoting tissue adhesion to soft tissue implants Method for promoting tissue adhesion to soft tissue implants

1988-03-16

1989-07-11

Cannon, Alan W.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

623 66, 427 2, A61F 202

Patent

active

048468347

ABSTRACT:
A soft tissue implant comprises a flexible main body portion, having tissue-facing surfaces and a thin layer of pure titanium covering the tissue-facing surfaces. A method of promoting tissue adhesion of a soft tissue host to the tissue-facing surfaces of a soft tissue implant comprising a strip of polyethylene terephthalate velour comprises the steps of cleaning the strip with a low-residue detergent and rinsing same with fresh distilled water; refluxing the strip in distilled water for one hour at a temperature of less than 30.degree. C.; drying the strip in a room-temperature desicator for several days; sterilizing the strip and packaging same; degasing the strip and storing same in a dust-free environment; removing the strip from the packaging and mounting the strip in a vacuum evaporator at an approximate angle of incidence of 90.degree. from a pure titanium metal evaporant; evacuating the vacuum evaporator to a vacuum of about 2.times.10.sup.-5 Torr; evaporating the titanium by direct resistence heating same; coating the strip with a layer of pure titanium on the order of one micron thick; and resterilizing and implanting the titanium-coated strip into the tissue host.

REFERENCES:
patent: 3557795 (1971-01-01), Hirsch
patent: 3677795 (1972-07-01), Bokros et al.
patent: 3952334 (1976-04-01), Bokros et al.
patent: 4149277 (1979-04-01), Bokros
patent: 4272855 (1981-06-01), Frey
patent: 4374669 (1983-02-01), MacGregor
patent: 4531916 (1985-07-01), Scantlebury et al.
patent: 4588667 (1986-05-01), Jones et al.

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