Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Blood
Patent
1990-05-18
1993-01-12
Rosen, Sam
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Blood
514 2, A61K 3514
Patent
active
051788837
ABSTRACT:
Platelet enriched plasma is produced from blood. The platelets are activated by thrombine which causes therelease of platelet-derived growth and angiogenesis factors. A carrier such as a microcrystalline collagen is added to produce a wound-treating salve. The composition is applied directly to wounds and initiates healing in nonhealing wounds as well as accelerating normal wound-healing by increasing vascularization, stimulating fibroblast mitrosis and migration, and increasing collagen synthesis by fibroblasts. The composition is also applied to tissue to facilitate the growth of hair.
REFERENCES:
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The Medical Business Journal, "Small Companies--Angio-Medical Corp.", Apr. 15, 1987.
Scrip, "Angio-Medical's Initial Offering", No. 1191, p. 9, Mar. 27, 1987.
Banda, M., et al., Proc. Nat'l Acad. Sci. USA, "Isolation of a Nonmitogenic Angiogenesis Factor From Wound Fluid", vol. 79, pp. 7773-7777 (Dec. 1982).
Grotendorst, G., et al., Surg. Sci. Serv., J. Trauma, vol. 24 (9 Suppl.), pp. 49-55 (1984).
Grotendorst, G., et al., Surg. Sci. Serv. (Soft and Hard Tissue Repair), "Molecular Mediators of Tissue Repair", vol. 2, pp. 20-40 (1984).
Scher et al.--Chem. Abst. vol. 102 (1985) p. 161,144q.
Curative Technologies, Inc.
Regents of the University of Minnesota
Rosen Sam
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