Method for proliferating V.gamma.2V.delta.2 T cells

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514106, 514134, 558155, 558156, 435375, 435384, C12N 502, C12N 506, A61K 3166, C07F 902

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056396538

ABSTRACT:
This invention is directed to a method for stimulating the proliferation of V.gamma.2V.delta.2 T cells comprising contacting V.gamma.2V.delta.2 T cells with a V.gamma.2V.delta.2 T cell proliferation stimulating amount of a compound selected from the group consisting of a monoalkyl phosphate and an alkenyl pyrophosphate.

REFERENCES:
Cuthbert, J.A. et al., FASEB Journal, vol. 4(7), p. A1747, abs. #309 1990.
Chakrabarti, R. et al., The Journal of Biological Chemistry, vol. 266(19), pp. 12216-12222 1991.
Tanaka, Y. et al., Nature, vol. 375(6527), pp. 155-158 May 1995.
Burk, M.R. et al., Eur. J. Immunol., vol. 25(7), pp. 2052-2058 1995.
Morita, C.T. et al., Immunity, vol. 3(4), pp. 495-507 Oct. 1995.

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