Method for proliferating V.gamma.2V.delta.2 T cells

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 45, 514 46, 514 48, 514 49, 514 52, 514814, 514825, 514885, 514895, 514908, A61K31/70

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059027932

ABSTRACT:
This invention is directed to a method for stimulating, the proliferation of V.gamma.2V.delta.2 T cells comprising contacting V.gamma.2V.delta.2 T cells with a V.gamma.2V.delta.2 T cell proliferation stimulating amount of a compound selected from the group-consisting of a monoalkyl phosphate, a hydroxy monoalkyl phosphate, a carboxy monoalkyl phosphate, a monoalkyl pyrophosphate, an alkenyl pyrophosphate, a .gamma.-monoalkyl nucleoside triphosphate, a .gamma.-monoalkyl deoxnucleoside triphosphate, a .gamma.-alkenyl nucleoside triphosphate, and a .gamma.-alkenyl deoxynucleoside triphosphate.

REFERENCES:
Tao et al., Antiviral Research vol. 12, pp. 269-278, 1989.
Tanaka et al., Proc. Natl. Acad. Sci. USA, 91:8175-8179, 1994.
Tanaka et al., Nature, 375:155-158, 1995.

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