Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-06-13
1989-04-18
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514970, A61K 3144
Patent
active
048228087
ABSTRACT:
A method for producing a stable preparation containing nicorandil, a saturated higher aliphatic acid or a saturated higher alcohol which is solid at ordinary temperatures, and optionally, an organic acid such as fumaric acid, oxalic acid, salicylic acid, tartaric acid or glutaric acid is disclosed.
Nicorandil is useful as a curative for various types of angina pectoris. However, it is unstable in humid conditions and under the compressive pressure exerted by punching operations in tablets making and, therefore, the development of a stable nicorandil preparation has been desired.
REFERENCES:
patent: 3168438 (1965-02-01), Halpern
patent: 3332848 (1967-07-01), Clifton
patent: 4200640 (1980-04-01), Nagano et al.
patent: 4323577 (1982-04-01), Ohkuma et al.
patent: 4382091 (1983-05-01), Benjamin et al.
patent: 4454108 (1984-06-01), Iida et al.
patent: 4490377 (1984-12-01), Chewhan
patent: 4565824 (1986-01-01), Wehinger et al.
Chem. Abst. 88:22652h (1978)-Nagano et al.
Chem. Abst. 99:58932r (1983)-Chugai Pharm.
Iida Yoshimitsu
Sumida Shuji
Chugai Seiyaku Kabushiki Kaisha
Robinson Douglas W.
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