Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-01-21
1989-02-07
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514960, 514970, A61K 3144
Patent
active
048032131
ABSTRACT:
A method for producing a stable pharmaceutical preparation containing nicorandil as an active ingredient is disclosed. The stable preparation is produced by mixing nicorandil, one or more finely comminuted sugars, and/or one or more powdery organic acids.
Nicorandil which is useful as a curative for various types of angina pectoris is not stable against the compressive pressure exerted by punching operations in tabelt making or against moisture.
The preparation of nicorandil manufactured by this invention is very stable and useful in clinical applications.
REFERENCES:
patent: 3168438 (1965-02-01), Halpern
patent: 3332848 (1967-07-01), Clifton
patent: 3577491 (1971-02-01), Cox
patent: 4200640 (1980-08-01), Nagano et al.
patent: 4323577 (1982-04-01), Ohkuma et al.
patent: 4382091 (1983-05-01), Benjamin et al.
patent: 4490377 (1984-12-01), Chowhan
patent: 4565824 (1986-01-01), Wehinger et al.
Chem. Abst. 88:22652h (1978)-Nagano et al.
Chem. Abst. 99: 58932v (1983)-Chugai Pharm.
Iida Yoshimitsu
Sumida Shuji
Terazono Takashi
Chugai Seiyaku Kabushiki Kaisha
Robinson Douglas W.
LandOfFree
Method for production of stable nicorandil preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for production of stable nicorandil preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for production of stable nicorandil preparation will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1085026