Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Patent
1998-04-24
2000-01-11
Moezie, F. T.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
435363, 435366, 435384, 435387, 435405, 435406, 435325, 435395, 435402, 536 231, C12N 500
Patent
active
060135212
ABSTRACT:
A method for producing a neuroblast and a cellular composition comprising an enriched population of neuroblast cells is provided. Also disclosed are methods for identifying compositions which affect neuroblasts and for treating a subject with a neuronal disorder, and a culture system for the production and maintenance of neuroblasts.
REFERENCES:
patent: 5270191 (1993-12-01), McKay et al.
patent: 5411883 (1995-05-01), Boss et al.
patent: 5514552 (1996-05-01), Rosner et al.
patent: 5766948 (1998-06-01), Gage et al.
Maisonpierre et al., "Neurotrophin-3: A Neurotrophic Factor Related to NGF and BDNF", Science, vol. 247, Part I, pp. 1446-1451 (1990).
Saneto et al., "Neuronal and glial cells: cell culture of the central nervous system", Cell Culture of the CNS, pp. 27-63, published 1987.
Cattaneo et al.,"Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor", Nature, vol. 347, pp. 762-765 (1990).
Walicke et al., "Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension", Proc. Natl. Acad. Sci. USA, vol. 83, pp. 3012-3016 May, 1986.
Piszczkiewicz et al., "Proliferation and Survival of Rat Sensory Neuron Precursors in Vitro", Soc. For Neuroscience, Abstract, 19 (Part 2) p. 1709 (1993).
DiCicco et al., "Insulin growth factors regulate the mitotic cycle in cultured rat sympathetic neuroblasts", Proc. Natl. Acad. Sci. USA, vol. 85, pp. 4066-4070, Jun. 1988.
Ray et al, "Proliferation, differentiation, and long-term culture of primary hippocampal neurons", PNAS, 90(8), pp. 3602-3606 (Apr. 1993).
Gensburger et al., "Brain basic fibroblast growth factor stimulates the proliferation of rat neuronal precursor cells in vitro", Biosis Abstract, FEBS Letter, 217(1) pp. 1-5 (1987).
Pincus et al., "Vasoactive intestinal peptide regulate mitosis, differentiation and survival of cultured symphathetic neuroblasts", Nature, vol. 343, pp. 564-567 (1990).
Calof et al., "Identification of a Proliferative Neuronal Precursor Cell in Sultures of a Mammalian . . . , " J. Cell Biol., 107 (6 Part 3) 510A (1988).
Chan et al.,J. of Cellular Biochemistry, 45:252-257, 1991.
Lendahl et al., TINS, vol. 13, No. 4, 133-137, 1990.
Gage Fred H.
Ray Jasodhara
Haile, Ph.D. Lisa A.
Moezie F. T.
University of California
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