Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1981-09-08
1984-06-05
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435123, 4351721, 435934, 735 68, C12P 1704, C12P 1702, C12N 1500, C12R 181
Patent
active
044528914
ABSTRACT:
Mycophenolic acid is produced by aerobically culturing in a culture medium a mutant of the genus Penicillium capable of producing mycophenolic acid, said mutant being resistant to clofibrat, and recovering the mycophenolic acid which accumulates in the culture medium.
REFERENCES:
patent: 4115197 (1978-09-01), Queener et al.
Birch, "Biosynthesis of some Monobenzenoid Quinones" Ciba Foundation Symposium, Quinones Electron Transport 1960 pp. 233-243 Chem. Abstracts 56: 9220i.
Cohen et al, "Effects of Clofibrate on Sterol Metabolism in the Rat" Biochemica et Biophysica Acta 369 (1974) pp. 79-85.
Andressen et al, "Nicotinamide-Adenine Dinucleotide Phosphate Dependant Formate Kehydrogenase from Clostridium Thermoaceticum" Journal of Bacteriology 120(1) (1974) pp. 6-14 Chemical Abstracts 81: 165365h.
Van Dijk et al, "Purification and Properties of Hydrogenase from Megasphaera Elsdenii" European Journal of Biochemistry 102(2) (1979) pp. 317-330 Chem. Abstracts 92: 89805m.
Ishikawa Takehiko
Kida Takao
Shibai Hiroshiro
Ajinomoto Company Incorporated
Tarcza John E.
Wiseman Thomas G.
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