Method for production of l-threonine

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435840, 4352521, 435280, C12P 1308, C12N 120

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active

050195034

ABSTRACT:
A method for producting L-threonine is described, comprising subjecting L- or DL-homoserine to enzymatic reaction in an aqueous medium in the presence of cells of biotin-requiring microorganisms belonging to the genus Brevibacterium and harvesting L-threonine from the reaction mixture.

REFERENCES:
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patent: 3527671 (1970-09-01), Zenk
Dunmenil et al., Eur. J. Appl. Microbiol., vol. 1, pp. 213-220, 1975.
Lynn et al., In Amino Acids Biosynthesis and Genetic Regulation, 1983, Addison-Wesley.
Goodfellow et al. The Biology of Actinomycetes 1984, Academic Press, pp. 77-79.
Bergey's Manual of Systematic Bacteriology, 1986, Williams and Wilkins, p. 1274.
Chemical Abstracts, vol. 99, Par 23, 5th Dec. 1983, p. 614, Abst. No. 193197v, Columbus, Ohio, U.S. & JP-A-58 129 990 Mar. 8, 1983.
Chemical Abstracts, vol. 85, Part II, 13th Jan. 1976, p. 411, Abstract No. 76311c, Columbus, Ohio, U.S., G. Dumenil et al.: Bioconversion from DL-Homoserine to L-Threonine., 1975, 1(3) 221-31.
Chemical Abstracts, vol. 56, Part 12, 10th Dec. 1962, p. 1962, Abstract No. 14746b, Columbus Ohio, U.S.; & JP-A-2 896/61 (Nissin Flour Milling Co., Ltd.) 11-04-1961.
Suzuki et al., International Journal of Systematic Bacteriology, vol. 31, pp. 131-138 (1981).

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