Method for production of 3-formyl-tetrahydrofuran

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D30712

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058409289

ABSTRACT:
3-Formyltetrahydrofuran is prepared by reacting 2,5-dihydrofuran with hydrogen and carbon monoxide in the presence of a group VIII metal compound and tris(2-t-butyl-5-methylphenyl) phosphite.

REFERENCES:
patent: 4376208 (1983-03-01), Vietti
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Weinheimer et al, "Rearrangement of Diphenan to 9, 10-dihydro-9-Phenanthrol by Potassium Amide and Dehydration to Phenanthrene. Results with 1,8-Naphthalan, Phthalan, and 2,5-Dihydrofuran", Journal of Organic Chemistry, vol. 18, pp. 801-805 (1953).
Barry et al, "Tripheylphosphine-Tetrachloromethane Promoted Chlorination and Cyclodehydratin of Simple Diols", Journal of Organic Chemistry, vol. 46, pp. 3361-3364 (1981).
Polo et al, "Regioselective Hydroformulation of Cyclic Vinyl and Allyl Ethers with Rhodium Catalysts. Crucial Influence of the Size of the Phosphorus Cocatalyst", Organometallics, vol. 11, pp. 3525-3533 (1992).
Poloet al, "Low-Pressure Selective Hydroformylation of 2,3- and 2,5-Dihydrofuran with a Rhydium Catalyst. Unexpected Influence of the Auxillary Ligand Tris(o-t-burylphenyl)Phosphite", J. Chem. Soc., Chem. Commun., pp. 600-601 (1990).
Fernandez et al, "Synthesis of Acetals from Alkenes by One-Pot Hydroformylation-Transacetalization Reactions Catalysed by Rhodium Complexes and Pyridnium p-Toluenesulphonate", Tetrahedron Letters, vol. 35, No. 15, pp. 2361-2364 (1994).

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