Method for production of 2-oxyimino-3-oxobutyric acids

Details Method for production of 2-oxyimino-3-oxobutyric acids Method for production of 2-oxyimino-3-oxobutyric acids

1989-01-11

1990-05-22

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

548342, 560121, 560123, 560124, 560125, 560168, 562503, 562505, 562506, 562507, C07C13100

Patent

active

049279645

ABSTRACT:
An advantageous method of producing in large amounts on a commercial scale 2-substituted oxyimino-3-oxobutyric acids, which are useful as intermediates in the synthesis of e.g. aminothiazole cephalosporins, is characterized by reacting a tert-butyl 2-substituted oxyimino-3-oxobutyrate with a hydrogen halide in an anhydrous organic solvent.

REFERENCES:
patent: 4107380 (1978-08-01), Wiesman
patent: 4191673 (1980-04-01), Wiesman

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