Method for producing α-bisabolol from farnesol

Details Method for producing α-bisabolol from farnesol Method for producing α-bisabolol from farnesol

2006-10-26

2009-11-24

Witherspoon, Sikarl A (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

Reexamination Certificate

active

07622617

ABSTRACT:
The present invention relates to a process for preparing α-bisabolol, comprising the reaction of farnesol in the presence of a ketone, of a sulfonic acid and of a further strong acid.

REFERENCES:
patent: 60-120828 (1985-06-01), None
patent: WO-2004/003301 (2004-01-01), None
patent: WO-2004/033401 (2004-04-01), None
Fourneron, J-D, et al., “Sur la stéréochimie de la cyclisation du nérolidol en α-bisabolol”, Bulletin de la Societe Chimlque de France Masson, 1980, vol. 2, No. 9/10, pp. 387-392.
Fourneron, J-D, et al., “The Stereochemistry of the Cyclization of Nerolidol to α-Bisabolol”, Tetrahedron, 1967, vol. 24, No. 2, pp. 859-876, English Translation of CA.
Gutsche, C.D., et al., “Acid-catalyzed Cyclization of Farnesol and Nerolidol”, Tetrahedron, 1968, vol. 24, pp. 859-876.

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