Method for producing thioctic acid

Details Method for producing thioctic acid Method for producing thioctic acid

2007-04-24

2007-04-24

Lambkin, Deborah C. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

10501729

ABSTRACT:
The invention relates to a method for producing pure racemic, R- or S-thioctic acid or mixtures thereof by reacting 6,8-disubstituted octanoic acid or their salts or esters with sulfides, sulfur or sulfites.

REFERENCES:
patent: 4797298 (1989-01-01), Brennan et al.
patent: 6013833 (2000-01-01), Gewald et al.
patent: 6229042 (2001-05-01), Gewald et al.
patent: 6288106 (2001-09-01), Pearson et al.
patent: 6313164 (2001-11-01), Fujita et al.
patent: 6441024 (2002-08-01), Klatt et al.
patent: 6462202 (2002-10-01), Schuhbauer et al.
patent: 6844449 (2005-01-01), Laban et al.
patent: 6844450 (2005-01-01), Salvi et al.
patent: 6864374 (2005-03-01), Villani et al.
patent: 7030251 (2006-04-01), Laban et al.
patent: 7109362 (2006-09-01), Klatt et al.
patent: 195 33 881 (1997-03-01), None
patent: 196 01 787 (1997-07-01), None
patent: 197 09 069 (1998-09-01), None
Bulman Page PC:, “An enatioselective synthesis of R-(+)-alpha lipoic acid”, Journal of Chemical Society Perkin Transactions I 1999, XP009010605 USA, pp. 1615-1618.
Gopalan AS et al., “Baker's yeast reduction of alkyl 6-chloro-3-oxohexanoates: synthesis of (R)-(+)-alpha lipoic acid”, Journal of Chemical Society Perkin Transactions I 1990, XP009010601 USA, pp. 1897-1900.
Brookes MH et al., “Synthesis of alpha-(R)-and alpha-(S)-lipoic acid from (S)-malic acid”, Journal of Chemical Society Perkin Transactions I 1988, XP009010600 USA, pp. 11.
Dhar P et al., “Piperidinium tetrathiothungstate as sulfur transfer reagent: synthesis of cyclic disulfides”, Journal of Organic Chemistry, 57, 1992, XP002241606 USA, pp. 1699-1702.
Crump DR, “Synthesis of (2S)-2-propylthietan”, Australian Journal of Chemistry, vol. 35, 1982,, pp. 1945-1948, XP002241607 Australia.

Affiliated with

Also associated with

Rating

Method for producing thioctic acid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for producing thioctic acid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing thioctic acid will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3801152