Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Reexamination Certificate
2007-11-06
2007-11-06
Swartz, Rodney P (Department: 1645)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
C424S093100, C424S184100, C424S234100, C424S257100, C435S041000, C435S069100, C435S071100, C435S440000, C536S023100, C536S023700
Reexamination Certificate
active
10545849
ABSTRACT:
A method for producing target proteins by deleting or amplifying ibpA and/or ibpB genes coding for inclusion body-associated proteins. Two methods for producing target proteins using ibpA and/or ibpB genes coding for inclusion body-associated proteins ofE. coliare described. The first method enhances the secretory production and activity of target proteins using ibpA and/or ibpB genes-deleted bacteria. The second method enhances the production of target proteins in the cytoplasm and also converts the target proteins from soluble form to insoluble inclusion body, using ibpA and/or ibpB gene-amplified bacteria.
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Han Mee Jung
Lee Sang Yup
Park Si Jae
Hultquist Steven J.
Intellectual Property / Technology Law
Korea Advanced Institute of Science and Technology
Reynolds Kelly K.
Swartz Rodney P
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