Method for producing tablets from plant extracts

Details Method for producing tablets from plant extracts Method for producing tablets from plant extracts

2002-07-15

2008-05-20

Tate, Christopher R (Department: 1655)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

C424S730000

Reexamination Certificate

active

07374784

ABSTRACT:
In a method for the production of tablets from plant extracts such as St. John's wort extract with an extract content of 80%, the extract treated on a conveyor dryer is compacted after adding 1% of silicon dioxide, and a granulate with a defined particle size distribution and therefore a defined surface area is produced from the compactate. To achieve a high rate of decomposition and active agent release with a low adjuvant content and high extract content, a combination of blasting agents including sodium hydrogencarbonate and two other, lower-dosed blasting agents such as croscarmellose sodium and sodium carboxymethyl starch—among other adjuvants—is added. The method results in a tablet suitable for oral administration containing 900 mg of St. John's wort extract.

REFERENCES:
patent: 6680072 (2004-01-01), Kuper et al.
patent: 0 530 833 (1993-03-01), None
patent: WO 99 32090 (1999-07-01), None
patent: WO 00 30605 (2000-06-01), None

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