Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1994-08-08
1995-11-28
Draper, Garnette D.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435 691, 435 6952, 435 704, 4352523, 4353261, 424 9321, C12N 1512, C12N 510
Patent
active
054707307
ABSTRACT:
The present invention relates to cytotoxic T lymphocytes (CTLs) which have been converted to a helper T cell independent phenotype by introducing a recombinant expression vector encoding IL-1 receptor into the CTL. The resulting CTLs have the ability to grow or function independent of T cell help.
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Greenberg Phillip D.
Overell Robert W.
Draper Garnette D.
Fred Hutchinson Cancer Research Center
Immunex
Ulm John D.
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